![]() The reactogenicity and adverse event profile observed after the booster dose was generally similar to that observed following dose 2 of the initial 2-dose regimen, which suggests no potentiation of reactogenicity or any new safety signals arising from administration of a third dose. If a person has a severe allergic reaction after getting a shot of an mRNA COVID-19 vaccine (either Pfizer-BioNTech or Moderna), that person should not get another shot of that vaccine. Anaphylaxis is treatable if recognized early and treated promptly. However, this reaction after the first dose is not a contraindication for the administration of the second dose.Ĭases of anaphylaxis to the mRNA COVID-19 vaccines are very rare - currently estimated to occur in 2.5 to 11.1 cases per 1 million doses, largely in individuals with a history of allergy. They usually resolve in about 5 days, but in some cases they can persist up to 21 days. Common side effects can include: Pain on the leg or arm where the shot was given Swollen lymph nodes Irritability or crying Sleepiness Loss of appetite. A third primary series dose of the Moderna COVID. This reaction may appear earlier after administration of the second dose. The Moderna COVID-19 Vaccine is administered as a primary series of two doses (0.5 mL each) 1 month apart to individuals 18 years of age or older. This type of reaction would NOT be considered. Myocarditis and pericarditis are mild in most cases and resolve with treatment and rest.ĭelayed skin reactions near the injection site have also been described, which occur about 7 days (between 2 and 12 days) after receiving the vaccine and have been described as oedematous, pruritic, and painful plaques. A common, known (intended) effect of orally administered polyethylene glycol is abdominal discomfort and diarrhea. These cases occurred mainly in the 14 days following vaccination, with greater frequency after the second dose of vaccination, and more commonly in younger men. ![]() This can last for around 10 days, but if it lasts longer see your doctor. In addition, very rare cases of myocarditis and pericarditis (inflammation of the heart muscle or membrane around the heart) have been observed. An uncommon side effect is swollen glands in the armpit or neck on the same side as the arm where you had the vaccine. These reactions are more common after the second dose and their frequency decreases with age. These reactions are mostly mild or moderate and transient, disappearing a few days after vaccination. The most common side effects are pain at the injection site (92%), fatigue (70%), headache (64.7%), myalgias (muscle pain) (61.5%), arthralgias (joint stiffness) (46.4%), chills (45.4%), nausea/vomiting (23%), fever (15.5%) and swelling at the injection site (14.7%).
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